BDBM50313307 (1R,5S,E)-8-(4-tert-butylphenylsulfonyl)-8-azabicyclo[3.2.1]octan-3-one O-benzyl oxime::CHEMBL1080557

SMILES: CC(C)(C)c1ccc(cc1)S(=O)(=O)N1[C@H]2CC[C@@H]1C\C(C2)=N\OCc1ccccc1

InChI Key: InChIKey=NNQZXUXKOLWKBN-LINBVKNMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50313307 ((1R,5S,E)-8-(4-tert-butylphenylsulfonyl)-8-azabicy...) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1[C@H]2CC[C@@H]1C\C(C2)=N\OCc1ccccc1 |r,THB:21:19:13:16.15| Show InChI InChI=1S/C24H30N2O3S/c1-24(2,3)19-9-13-23(14-10-19)30(27,28)26-21-11-12-22(26)16-20(15-21)25-29-17-18-7-5-4-6-8-18/h4-10,13-14,21-22H,11-12,15-17H2,1-3H3/b25-20-/t21-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	989	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cortisone from mouse 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assay				Bioorg Med Chem Lett 20: 1551-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.082 BindingDB Entry DOI: 10.7270/Q2NV9JC3
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50313307 ((1R,5S,E)-8-(4-tert-butylphenylsulfonyl)-8-azabicy...) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1[C@H]2CC[C@@H]1C\C(C2)=N\OCc1ccccc1 |r,THB:21:19:13:16.15| Show InChI InChI=1S/C24H30N2O3S/c1-24(2,3)19-9-13-23(14-10-19)30(27,28)26-21-11-12-22(26)16-20(15-21)25-29-17-18-7-5-4-6-8-18/h4-10,13-14,21-22H,11-12,15-17H2,1-3H3/b25-20-/t21-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cortisone from human 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assay				Bioorg Med Chem Lett 20: 1551-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.082 BindingDB Entry DOI: 10.7270/Q2NV9JC3
					More data for this Ligand-Target Pair