BDBM50313391 (4aS,5R,10bS)-5-phenyl-9-(trifluoromethyl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinoline::CHEMBL1089057

SMILES: FC(F)(F)c1ccc2N[C@H]([C@@H]3CCCO[C@@H]3c2c1)c1ccccc1

InChI Key: InChIKey=DFSNLFKINFSIFO-WBAXXEDZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313391   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50313391 ((4aS,5R,10bS)-5-phenyl-9-(trifluoromethyl)-3,4,4a,...) Show SMILES FC(F)(F)c1ccc2N[C@H]([C@@H]3CCCO[C@@H]3c2c1)c1ccccc1 |r| Show InChI InChI=1S/C19H18F3NO/c20-19(21,22)13-8-9-16-15(11-13)18-14(7-4-10-24-18)17(23-16)12-5-2-1-3-6-12/h1-3,5-6,8-9,11,14,17-18,23H,4,7,10H2/t14-,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of ATPase activity of human recombinant EG5 assessed as ATP hydrolysis by pyruvate kinase-lactate dehydrogenase coupled assay				Bioorg Med Chem Lett 20: 1491-5 (2010) Article DOI: 10.1016/j.bmcl.2010.01.110 BindingDB Entry DOI: 10.7270/Q2KD1ZWN
					More data for this Ligand-Target Pair