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SMILES: [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1sccc1-[#7]S(=O)(=O)c1cccc(-[#7])c1)-[#6](-[#8])=O

InChI Key: InChIKey=RAZZEZZYCVSMLQ-ZDUSSCGKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313485   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropilin-1


(Homo sapiens (Human))		BDBM50313485
PNG
((S)-2-{[3-(3-Amino-benzenesulfonylamino)-thiophene...)
Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1sccc1-[#7]S(=O)(=O)c1cccc(-[#7])c1)-[#6](-[#8])=O |r|
Show InChI InChI=1S/C17H22N6O5S2/c18-10-3-1-4-11(9-10)30(27,28)23-12-6-8-29-14(12)15(24)22-13(16(25)26)5-2-7-21-17(19)20/h1,3-4,6,8-9,13,23H,2,5,7,18H2,(H,22,24)(H,25,26)(H4,19,20,21)/t13-/m0/s1
PDB
MMDB

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Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Domainex Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cells

J Med Chem 53: 2215-26 (2010)


Article DOI: 10.1021/jm901755g
BindingDB Entry DOI: 10.7270/Q2154H62
More data for this
Ligand-Target Pair