BDBM50313611 5'-Trifluoromethoxy-1H,1'H-[2,3']biindolylidene-3,2'-dione 3-oxime::CHEMBL1083839

SMILES: FC(F)(F)Oc1ccc2NC(=O)C(c2c1)c1[nH]c2ccccc2c1N=O

InChI Key: InChIKey=XULONIVOENCMLI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50313611 (5'-Trifluoromethoxy-1H,1'H-[2,3']biindolylidene-3,...) Show SMILES FC(F)(F)Oc1ccc2NC(=O)C(c2c1)c1[nH]c2ccccc2c1N=O Show InChI InChI=1S/C17H10F3N3O3/c18-17(19,20)26-8-5-6-12-10(7-8)13(16(24)22-12)15-14(23-25)9-3-1-2-4-11(9)21-15/h1-7,13,21H,(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of FLT3 by HTRF assay				Bioorg Med Chem Lett 20: 2033-7 (2010) Article DOI: 10.1016/j.bmcl.2010.01.039 BindingDB Entry DOI: 10.7270/Q29W0GF0
					More data for this Ligand-Target Pair