BDBM50313664 CHEMBL1077218::N-(6-chloro-5-(furan-3-yl)-1H-indazol-3-yl)butyramide

SMILES: CCCC(=O)Nc1n[nH]c2cc(Cl)c(cc12)-c1ccoc1

InChI Key: InChIKey=KOUMERRMZIVPFK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313664   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50313664 (CHEMBL1077218 | N-(6-chloro-5-(furan-3-yl)-1H-inda...) Show SMILES CCCC(=O)Nc1n[nH]c2cc(Cl)c(cc12)-c1ccoc1 Show InChI InChI=1S/C15H14ClN3O2/c1-2-3-14(20)17-15-11-6-10(9-4-5-21-8-9)12(16)7-13(11)18-19-15/h4-8H,2-3H2,1H3,(H2,17,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 1985-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.114 BindingDB Entry DOI: 10.7270/Q2QN66XJ
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50313664 (CHEMBL1077218 | N-(6-chloro-5-(furan-3-yl)-1H-inda...) Show SMILES CCCC(=O)Nc1n[nH]c2cc(Cl)c(cc12)-c1ccoc1 Show InChI InChI=1S/C15H14ClN3O2/c1-2-3-14(20)17-15-11-6-10(9-4-5-21-8-9)12(16)7-13(11)18-19-15/h4-8H,2-3H2,1H3,(H2,17,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta by kinetic assay				Bioorg Med Chem Lett 20: 2344-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.132 BindingDB Entry DOI: 10.7270/Q2SB45WF
					More data for this Ligand-Target Pair