BDBM50313741 4'-(2-(5-(cyclopentylmethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid::CHEMBL1084942

SMILES: OC(=O)c1ccccc1-c1ccc(CCc2ncc(CC3CCCC3)[nH]2)cc1

InChI Key: InChIKey=OENIXTHWZWFYIV-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313741   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bombesin receptor subtype-3 (Mus musculus)	BDBM50313741 (4'-(2-(5-(cyclopentylmethyl)-1H-imidazol-2-yl)ethy...) Show SMILES OC(=O)c1ccccc1-c1ccc(CCc2ncc(CC3CCCC3)[nH]2)cc1 Show InChI InChI=1S/C24H26N2O2/c27-24(28)22-8-4-3-7-21(22)19-12-9-17(10-13-19)11-14-23-25-16-20(26-23)15-18-5-1-2-6-18/h3-4,7-10,12-13,16,18H,1-2,5-6,11,14-15H2,(H,25,26)(H,27,28)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonistic activity at mouse BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assay				Bioorg Med Chem Lett 20: 1913-7 (2010) Article DOI: 10.1016/j.bmcl.2010.01.154 BindingDB Entry DOI: 10.7270/Q2M045KD
					More data for this Ligand-Target Pair
BRS3 (Homo sapiens (Human))	BDBM50313741 (4'-(2-(5-(cyclopentylmethyl)-1H-imidazol-2-yl)ethy...) Show SMILES OC(=O)c1ccccc1-c1ccc(CCc2ncc(CC3CCCC3)[nH]2)cc1 Show InChI InChI=1S/C24H26N2O2/c27-24(28)22-8-4-3-7-21(22)19-12-9-17(10-13-19)11-14-23-25-16-20(26-23)15-18-5-1-2-6-18/h3-4,7-10,12-13,16,18H,1-2,5-6,11,14-15H2,(H,25,26)(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	133	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonistic activity at human BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assay				Bioorg Med Chem Lett 20: 1913-7 (2010) Article DOI: 10.1016/j.bmcl.2010.01.154 BindingDB Entry DOI: 10.7270/Q2M045KD
					More data for this Ligand-Target Pair