BDBM50313826 (+/-)-5-(1,1-Dioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-ylmethyl)-5-(4-fluoro-phenyl)-imidazolidine-2,4-dione::CHEMBL1087930

SMILES: Fc1ccc(cc1)C1(CN2Cc3ccccc3S2(=O)=O)NC(=O)NC1=O

InChI Key: InChIKey=NCEBBHOMOAWRPQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313826   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50313826 ((+/-)-5-(1,1-Dioxo-1,3-dihydro-1lambda*6*-benzo[d]...) Show SMILES Fc1ccc(cc1)C1(CN2Cc3ccccc3S2(=O)=O)NC(=O)NC1=O Show InChI InChI=1S/C17H14FN3O4S/c18-13-7-5-12(6-8-13)17(15(22)19-16(23)20-17)10-21-9-11-3-1-2-4-14(11)26(21,24)25/h1-8H,9-10H2,(H2,19,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of TACE by FRET assay				Bioorg Med Chem Lett 20: 1877-80 (2010) Article DOI: 10.1016/j.bmcl.2010.01.148 BindingDB Entry DOI: 10.7270/Q2F76CQ9
					More data for this Ligand-Target Pair