BDBM50313838 (R)-5-(4-hydroxyphenyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1090736

SMILES: COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(O)cc3)C(=O)c2c1

InChI Key: InChIKey=KYZRENMUIQDTHR-IBGZPJMESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313838   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50313838 ((R)-5-(4-hydroxyphenyl)-5-((6-methoxy-1-oxoisoindo...) Show SMILES COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(O)cc3)C(=O)c2c1 |r| Show InChI InChI=1S/C19H17N3O5/c1-27-14-7-2-11-9-22(16(24)15(11)8-14)10-19(17(25)20-18(26)21-19)12-3-5-13(23)6-4-12/h2-8,23H,9-10H2,1H3,(H2,20,21,25,26)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of TACE by FRET assay				Bioorg Med Chem Lett 20: 1877-80 (2010) Article DOI: 10.1016/j.bmcl.2010.01.148 BindingDB Entry DOI: 10.7270/Q2F76CQ9
					More data for this Ligand-Target Pair