BDBM50313974 (R)-N-(4-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)ethyl)phenyl)-5-methyl-2-(pyrrolidin-1-yl)benzamide::CHEMBL1078696

SMILES: Cc1ccc(N2CCCC2)c(c1)C(=O)Nc1ccc(CCNC[C@H](O)c2cccnc2)cc1

InChI Key: InChIKey=LHCFSNPXYUWJLQ-SANMLTNESA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50313974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50313974 ((R)-N-(4-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)...) Show SMILES Cc1ccc(N2CCCC2)c(c1)C(=O)Nc1ccc(CCNC[C@H](O)c2cccnc2)cc1 |r| Show InChI InChI=1S/C27H32N4O2/c1-20-6-11-25(31-15-2-3-16-31)24(17-20)27(33)30-23-9-7-21(8-10-23)12-14-29-19-26(32)22-5-4-13-28-18-22/h4-11,13,17-18,26,29,32H,2-3,12,14-16,19H2,1H3,(H,30,33)/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]cyanopindolol from human beta 2 adrenergic receptor expressed in CHO cells at 10 uM after 3 to 4 hrs by scintillation counter				Bioorg Med Chem Lett 20: 1895-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.130 BindingDB Entry DOI: 10.7270/Q2639QPK
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50313974 ((R)-N-(4-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)...) Show SMILES Cc1ccc(N2CCCC2)c(c1)C(=O)Nc1ccc(CCNC[C@H](O)c2cccnc2)cc1 |r| Show InChI InChI=1S/C27H32N4O2/c1-20-6-11-25(31-15-2-3-16-31)24(17-20)27(33)30-23-9-7-21(8-10-23)12-14-29-19-26(32)22-5-4-13-28-18-22/h4-11,13,17-18,26,29,32H,2-3,12,14-16,19H2,1H3,(H,30,33)/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]cyanopindolol from human beta 1 adrenergic receptor expressed in CHO cells at 10 uM after 3 to 4 hrs by scintillation counter				Bioorg Med Chem Lett 20: 1895-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.130 BindingDB Entry DOI: 10.7270/Q2639QPK
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50313974 ((R)-N-(4-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)...) Show SMILES Cc1ccc(N2CCCC2)c(c1)C(=O)Nc1ccc(CCNC[C@H](O)c2cccnc2)cc1 |r| Show InChI InChI=1S/C27H32N4O2/c1-20-6-11-25(31-15-2-3-16-31)24(17-20)27(33)30-23-9-7-21(8-10-23)12-14-29-19-26(32)22-5-4-13-28-18-22/h4-11,13,17-18,26,29,32H,2-3,12,14-16,19H2,1H3,(H,30,33)/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonistic activity at human beta3 adrenergic receptor expressed in CHO cells assessed as amount of cAMP released after 1 hr by fluorescence resonance...				Bioorg Med Chem Lett 20: 1895-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.130 BindingDB Entry DOI: 10.7270/Q2639QPK
					More data for this Ligand-Target Pair