BDBM50314000 3-(4-(2-fluorophenyl)piperazine-1-carbonyl)-8-mesityl-2-methyl-5,6-dihydroimidazo[1,2-a]pyrimidin-7(8H)-one::CHEMBL1088325

SMILES: Cc1nc2N(C(=O)CCn2c1C(=O)N1CCN(CC1)c1ccccc1F)c1c(C)cc(C)cc1C

InChI Key: InChIKey=ISYXQSJHBBCMFG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50314000 (3-(4-(2-fluorophenyl)piperazine-1-carbonyl)-8-mesi...) Show SMILES Cc1nc2N(C(=O)CCn2c1C(=O)N1CCN(CC1)c1ccccc1F)c1c(C)cc(C)cc1C Show InChI InChI=1S/C27H30FN5O2/c1-17-15-18(2)24(19(3)16-17)33-23(34)9-10-32-25(20(4)29-27(32)33)26(35)31-13-11-30(12-14-31)22-8-6-5-7-21(22)28/h5-8,15-16H,9-14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cells				Bioorg Med Chem Lett 20: 1905-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.127 BindingDB Entry DOI: 10.7270/Q24Q7V3F
					More data for this Ligand-Target Pair