BDBM50314009 CHEMBL1087166::N-(cyclopropylmethyl)-2,2,3,3,3-pentafluoro-N-((8-mesityl-2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidin-3-yl)methyl)propan-1-amine

SMILES: Cc1cc(C)c(N2CCCn3c(CN(CC4CC4)CC(F)(F)C(F)(F)F)c(nc23)C(F)(F)F)c(C)c1

InChI Key: InChIKey=SGFLNPLFTLQYGT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50314009 (CHEMBL1087166 | N-(cyclopropylmethyl)-2,2,3,3,3-pe...) Show SMILES Cc1cc(C)c(N2CCCn3c(CN(CC4CC4)CC(F)(F)C(F)(F)F)c(nc23)C(F)(F)F)c(C)c1 Show InChI InChI=1S/C24H28F8N4/c1-14-9-15(2)19(16(3)10-14)36-8-4-7-35-18(20(23(27,28)29)33-21(35)36)12-34(11-17-5-6-17)13-22(25,26)24(30,31)32/h9-10,17H,4-8,11-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cells				Bioorg Med Chem Lett 20: 1905-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.127 BindingDB Entry DOI: 10.7270/Q24Q7V3F
					More data for this Ligand-Target Pair