BDBM50314019 3-((5,6-dihydropyridin-1(2H)-yl)methyl)-8-mesityl-2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidine::CHEMBL1087172

SMILES: Cc1cc(C)c(N2CCCn3c(CN4CCC=CC4)c(nc23)C(F)(F)F)c(C)c1

InChI Key: InChIKey=YPYQSCMHNLMVBS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50314019 (3-((5,6-dihydropyridin-1(2H)-yl)methyl)-8-mesityl-...) Show SMILES Cc1cc(C)c(N2CCCn3c(CN4CCC=CC4)c(nc23)C(F)(F)F)c(C)c1 |c:16| Show InChI InChI=1S/C22H27F3N4/c1-15-12-16(2)19(17(3)13-15)29-11-7-10-28-18(14-27-8-5-4-6-9-27)20(22(23,24)25)26-21(28)29/h4-5,12-13H,6-11,14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	364	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cells				Bioorg Med Chem Lett 20: 1905-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.127 BindingDB Entry DOI: 10.7270/Q24Q7V3F
					More data for this Ligand-Target Pair