BDBM50314062 CHEMBL1092180::N-(3-(2-(2-(2-(dimethylamino)ethylamino)pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide

SMILES: CN(C)CCNc1cc(ccn1)-c1cc2nccc(-c3cccc(NC(=O)c4cccc(c4)C(F)(F)F)c3)n2n1

InChI Key: InChIKey=JJZMISIQDYXLAI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50314062 (CHEMBL1092180 | N-(3-(2-(2-(2-(dimethylamino)ethyl...) Show SMILES CN(C)CCNc1cc(ccn1)-c1cc2nccc(-c3cccc(NC(=O)c4cccc(c4)C(F)(F)F)c3)n2n1 Show InChI InChI=1S/C29H26F3N7O/c1-38(2)14-13-34-26-17-19(9-11-33-26)24-18-27-35-12-10-25(39(27)37-24)20-5-4-8-23(16-20)36-28(40)21-6-3-7-22(15-21)29(30,31)32/h3-12,15-18H,13-14H2,1-2H3,(H,33,34)(H,36,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of b-Raf				Bioorg Med Chem Lett 19: 6890-2 (2009) Article DOI: 10.1016/j.bmcl.2009.10.074 BindingDB Entry DOI: 10.7270/Q2C829F3
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