BDBM50314082 (S)-N1-((S)-1-((S)-1-((3S,11S,14S,20S,23S,32S,35S,41aS)-20-((1H-imidazol-4-yl)methyl)-3-((S)-4-amino-1-(2-((S)-2-carbamoylpyrrolidin-1-yl)-2-oxoethylamino)-1,4-dioxobutan-2-ylcarbamoyl)-23-benzyl-35-(4-hydroxybenzyl)-14-((R)-1-hydroxyethyl)-32-isobutyl-28,31-dimethyl-1,9,12,15,18,21,24,27,30,33,36,37-dodecaoxotetracontahydro-1H-pyrrolo[1,2-z][1,4,7,10,13,16,19,22,26,29,35]undecaazacyclononatriacontin-11-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-yl)-2-acetamidopentanediam::CHEMBL1089950

SMILES: CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O

InChI Key: InChIKey=GRNGOJKQKRCTFF-BGGXCMKMSA-N

Data: 1 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
IgG receptor FcRn large subunit p51 (Homo sapiens (Human))	BDBM50314082 ((S)-N1-((S)-1-((S)-1-((3S,11S,14S,20S,23S,32S,35S,...) Show SMILES CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O |r| Show InChI InChI=1S/C91H128N26O24/c1-49(2)36-68-88(139)108-60(37-54-26-28-56(120)29-27-54)77(128)90(141)117-35-17-25-67(117)87(138)107-57(81(132)111-64(41-70(93)122)80(131)102-46-74(126)116-34-16-24-66(116)78(94)129)22-13-14-32-98-71(123)42-65(112-84(135)62(39-53-20-11-8-12-21-53)110-82(133)58(23-15-33-99-91(95)96)106-83(134)59(104-51(4)119)30-31-69(92)121)86(137)113-76(50(3)118)89(140)100-44-72(124)105-63(40-55-43-97-48-103-55)85(136)109-61(38-52-18-9-7-10-19-52)79(130)101-45-73(125)114(5)47-75(127)115(68)6/h7-12,18-21,26-29,43,48-50,57-68,76,118,120H,13-17,22-25,30-42,44-47H2,1-6H3,(H2,92,121)(H2,93,122)(H2,94,129)(H,97,103)(H,98,123)(H,100,140)(H,101,130)(H,102,131)(H,104,119)(H,105,124)(H,106,134)(H,107,138)(H,108,139)(H,109,136)(H,110,133)(H,111,132)(H,112,135)(H,113,137)(H4,95,96,99)/t50-,57+,58+,59+,60+,61+,62+,63+,64+,65+,66+,67+,68+,76+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Syntonix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISA				J Med Chem 53: 1587-96 (2010) Article DOI: 10.1021/jm901128z BindingDB Entry DOI: 10.7270/Q23R0T1H
					More data for this Ligand-Target Pair
IgG receptor FcRn large subunit p51 (Homo sapiens (Human))	BDBM50314082 ((S)-N1-((S)-1-((S)-1-((3S,11S,14S,20S,23S,32S,35S,...) Show SMILES CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O |r| Show InChI InChI=1S/C91H128N26O24/c1-49(2)36-68-88(139)108-60(37-54-26-28-56(120)29-27-54)77(128)90(141)117-35-17-25-67(117)87(138)107-57(81(132)111-64(41-70(93)122)80(131)102-46-74(126)116-34-16-24-66(116)78(94)129)22-13-14-32-98-71(123)42-65(112-84(135)62(39-53-20-11-8-12-21-53)110-82(133)58(23-15-33-99-91(95)96)106-83(134)59(104-51(4)119)30-31-69(92)121)86(137)113-76(50(3)118)89(140)100-44-72(124)105-63(40-55-43-97-48-103-55)85(136)109-61(38-52-18-9-7-10-19-52)79(130)101-45-73(125)114(5)47-75(127)115(68)6/h7-12,18-21,26-29,43,48-50,57-68,76,118,120H,13-17,22-25,30-42,44-47H2,1-6H3,(H2,92,121)(H2,93,122)(H2,94,129)(H,97,103)(H,98,123)(H,100,140)(H,101,130)(H,102,131)(H,104,119)(H,105,124)(H,106,134)(H,107,138)(H,108,139)(H,109,136)(H,110,133)(H,111,132)(H,112,135)(H,113,137)(H4,95,96,99)/t50-,57+,58+,59+,60+,61+,62+,63+,64+,65+,66+,67+,68+,76+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	7.4	n/a
Syntonix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assay				J Med Chem 53: 1587-96 (2010) Article DOI: 10.1021/jm901128z BindingDB Entry DOI: 10.7270/Q23R0T1H
					More data for this Ligand-Target Pair
IgG receptor FcRn large subunit p51 (Homo sapiens (Human))	BDBM50314082 ((S)-N1-((S)-1-((S)-1-((3S,11S,14S,20S,23S,32S,35S,...) Show SMILES CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O |r| Show InChI InChI=1S/C91H128N26O24/c1-49(2)36-68-88(139)108-60(37-54-26-28-56(120)29-27-54)77(128)90(141)117-35-17-25-67(117)87(138)107-57(81(132)111-64(41-70(93)122)80(131)102-46-74(126)116-34-16-24-66(116)78(94)129)22-13-14-32-98-71(123)42-65(112-84(135)62(39-53-20-11-8-12-21-53)110-82(133)58(23-15-33-99-91(95)96)106-83(134)59(104-51(4)119)30-31-69(92)121)86(137)113-76(50(3)118)89(140)100-44-72(124)105-63(40-55-43-97-48-103-55)85(136)109-61(38-52-18-9-7-10-19-52)79(130)101-45-73(125)114(5)47-75(127)115(68)6/h7-12,18-21,26-29,43,48-50,57-68,76,118,120H,13-17,22-25,30-42,44-47H2,1-6H3,(H2,92,121)(H2,93,122)(H2,94,129)(H,97,103)(H,98,123)(H,100,140)(H,101,130)(H,102,131)(H,104,119)(H,105,124)(H,106,134)(H,107,138)(H,108,139)(H,109,136)(H,110,133)(H,111,132)(H,112,135)(H,113,137)(H4,95,96,99)/t50-,57+,58+,59+,60+,61+,62+,63+,64+,65+,66+,67+,68+,76+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	6.0	n/a
Syntonix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assay				J Med Chem 53: 1587-96 (2010) Article DOI: 10.1021/jm901128z BindingDB Entry DOI: 10.7270/Q23R0T1H
					More data for this Ligand-Target Pair