null

SMILES: CCOC(=O)\C=C\[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)OC(C)(C)C

InChI Key: InChIKey=BXXKSYCPDCBGPI-WPJHKJGHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314124   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314124 ((S,E)-ethyl 4-(tert-butoxycarbonylamino)-7-oxo-7-(...) Show SMILES CCOC(=O)\C=C\[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C33H38N2O5/c1-5-39-30(37)24-22-28(34-31(38)40-32(2,3)4)21-23-29(36)35-33(25-15-9-6-10-16-25,26-17-11-7-12-18-26)27-19-13-8-14-20-27/h6-20,22,24,28H,5,21,23H2,1-4H3,(H,34,38)(H,35,36)/b24-22+/t28-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay in presence of DTT				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314124 ((S,E)-ethyl 4-(tert-butoxycarbonylamino)-7-oxo-7-(...) Show SMILES CCOC(=O)\C=C\[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C33H38N2O5/c1-5-39-30(37)24-22-28(34-31(38)40-32(2,3)4)21-23-29(36)35-33(25-15-9-6-10-16-25,26-17-11-7-12-18-26)27-19-13-8-14-20-27/h6-20,22,24,28H,5,21,23H2,1-4H3,(H,34,38)(H,35,36)/b24-22+/t28-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair