null
SMILES: CCOC(=O)\C=C\[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1
InChI Key: InChIKey=RBIOEWRVNCMSBI-VRLHVHMNSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using low concentration of enzyme by standard fluorescence assay in presence of de... | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using high concentration of enzyme by standard fluorescence assay in presence of d... | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using low concentration of enzyme by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using high concentration of enzyme by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair |