null

SMILES: CCN(CC)C(=O)C1CCN(CC1)c1ccnc2n(C)cc(\C=C3/Oc4ccc(NC(=O)Nc5cccnc5)cc4C3=O)c12

InChI Key: InChIKey=WARFAAVACUFFOT-QRQIAZFYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314319   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50314319 ((Z)-N,N-diethyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin...) Show SMILES CCN(CC)C(=O)C1CCN(CC1)c1ccnc2n(C)cc(\C=C3/Oc4ccc(NC(=O)Nc5cccnc5)cc4C3=O)c12 Show InChI InChI=1S/C33H35N7O4/c1-4-39(5-2)32(42)21-11-15-40(16-12-21)26-10-14-35-31-29(26)22(20-38(31)3)17-28-30(41)25-18-23(8-9-27(25)44-28)36-33(43)37-24-7-6-13-34-19-24/h6-10,13-14,17-21H,4-5,11-12,15-16H2,1-3H3,(H2,36,37,43)/b28-17-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	308	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha				Bioorg Med Chem Lett 20: 2259-63 (2010) Article DOI: 10.1016/j.bmcl.2010.02.012 BindingDB Entry DOI: 10.7270/Q2TB1717
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50314319 ((Z)-N,N-diethyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin...) Show SMILES CCN(CC)C(=O)C1CCN(CC1)c1ccnc2n(C)cc(\C=C3/Oc4ccc(NC(=O)Nc5cccnc5)cc4C3=O)c12 Show InChI InChI=1S/C33H35N7O4/c1-4-39(5-2)32(42)21-11-15-40(16-12-21)26-10-14-35-31-29(26)22(20-38(31)3)17-28-30(41)25-18-23(8-9-27(25)44-28)36-33(43)37-24-7-6-13-34-19-24/h6-10,13-14,17-21H,4-5,11-12,15-16H2,1-3H3,(H2,36,37,43)/b28-17-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of mTOR				Bioorg Med Chem Lett 20: 2259-63 (2010) Article DOI: 10.1016/j.bmcl.2010.02.012 BindingDB Entry DOI: 10.7270/Q2TB1717
					More data for this Ligand-Target Pair