BDBM50314638 (E)-3-{3-Fluoro-4-[3-(1H-indol-3-yl)piperidin-1-ylmethyl]-phenyl}-N-hydroxyacrylamide::CHEMBL1093051

SMILES: ONC(=O)\C=C\c1ccc(CN2CCCC(C2)c2c[nH]c3ccccc23)c(F)c1

InChI Key: InChIKey=CDODDYUNBWYGOC-CSKARUKUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314638   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50314638 ((E)-3-{3-Fluoro-4-[3-(1H-indol-3-yl)piperidin-1-yl...) Show SMILES ONC(=O)\C=C\c1ccc(CN2CCCC(C2)c2c[nH]c3ccccc23)c(F)c1 Show InChI InChI=1S/C23H24FN3O2/c24-21-12-16(8-10-23(28)26-29)7-9-18(21)15-27-11-3-4-17(14-27)20-13-25-22-6-2-1-5-19(20)22/h1-2,5-10,12-13,17,25,29H,3-4,11,14-15H2,(H,26,28)/b10-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assay				J Med Chem 53: 2952-63 (2010) Article DOI: 10.1021/jm100007m BindingDB Entry DOI: 10.7270/Q20V8CZC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50314638 ((E)-3-{3-Fluoro-4-[3-(1H-indol-3-yl)piperidin-1-yl...) Show SMILES ONC(=O)\C=C\c1ccc(CN2CCCC(C2)c2c[nH]c3ccccc23)c(F)c1 Show InChI InChI=1S/C23H24FN3O2/c24-21-12-16(8-10-23(28)26-29)7-9-18(21)15-27-11-3-4-17(14-27)20-13-25-22-6-2-1-5-19(20)22/h1-2,5-10,12-13,17,25,29H,3-4,11,14-15H2,(H,26,28)/b10-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assay				J Med Chem 53: 2952-63 (2010) Article DOI: 10.1021/jm100007m BindingDB Entry DOI: 10.7270/Q20V8CZC
					More data for this Ligand-Target Pair