BDBM50314992 CHEMBL1092382::N-(4-(3-Bromophenylamino)quinolin-6-yl)propionamide
SMILES: CCC(=O)Nc1ccc2nccc(Nc3cccc(Br)c3)c2c1
InChI Key: InChIKey=UATWOAYHIISFBR-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50314992 (CHEMBL1092382 | N-(4-(3-Bromophenylamino)quinolin-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Genomics Centre of the Max Planck Society Curated by ChEMBL | Assay Description Inhibition of wild type EGFR by HTRF assay | J Med Chem 53: 2892-901 (2010) Article DOI: 10.1021/jm901877j BindingDB Entry DOI: 10.7270/Q2T43T7N | |||||||||||
More data for this Ligand-Target Pair |