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SMILES: CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1cccc(Cl)c1

InChI Key: InChIKey=RPEOVNFMEZECTP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315132 (4-(3-(3-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C20H21ClN4/c1-25-11-7-15(8-12-25)19-18(14-5-9-22-10-6-14)20(24-23-19)16-3-2-4-17(21)13-16/h2-6,9-10,13,15H,7-8,11-12H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39.2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315132 (4-(3-(3-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C20H21ClN4/c1-25-11-7-15(8-12-25)19-18(14-5-9-22-10-6-14)20(24-23-19)16-3-2-4-17(21)13-16/h2-6,9-10,13,15H,7-8,11-12H2,1H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair