BDBM50315141 CHEMBL1093969::isopropyl 4-((6-(4-(2-methoxyethyl)piperazin-1-yl)pyridin-3-yloxy)methyl)piperidine-1-carboxylate

SMILES: COCCN1CCN(CC1)c1ccc(OCC2CCN(CC2)C(=O)OC(C)C)cn1

InChI Key: InChIKey=NFOVJGIKZNDICV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50315141 (CHEMBL1093969 | isopropyl 4-((6-(4-(2-methoxyethyl...) Show SMILES COCCN1CCN(CC1)c1ccc(OCC2CCN(CC2)C(=O)OC(C)C)cn1 Show InChI InChI=1S/C22H36N4O4/c1-18(2)30-22(27)26-8-6-19(7-9-26)17-29-20-4-5-21(23-16-20)25-12-10-24(11-13-25)14-15-28-3/h4-5,16,18-19H,6-15,17H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor expressed in CHO-K1 cells cotransfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 2577-81 (2010) Article DOI: 10.1016/j.bmcl.2010.02.083 BindingDB Entry DOI: 10.7270/Q2WW7HT8
					More data for this Ligand-Target Pair