BDBM50315145 CHEMBL1088852::isopropyl 4-((6-(4-(butylsulfonyl)piperazin-1-yl)pyridin-3-yloxy)methyl)piperidine-1-carboxylate

SMILES: CCCCS(=O)(=O)N1CCN(CC1)c1ccc(OCC2CCN(CC2)C(=O)OC(C)C)cn1

InChI Key: InChIKey=ISIGLWUEDMGLON-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50315145 (CHEMBL1088852 | isopropyl 4-((6-(4-(butylsulfonyl)...) Show SMILES CCCCS(=O)(=O)N1CCN(CC1)c1ccc(OCC2CCN(CC2)C(=O)OC(C)C)cn1 Show InChI InChI=1S/C23H38N4O5S/c1-4-5-16-33(29,30)27-14-12-25(13-15-27)22-7-6-21(17-24-22)31-18-20-8-10-26(11-9-20)23(28)32-19(2)3/h6-7,17,19-20H,4-5,8-16,18H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor expressed in CHO-K1 cells cotransfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 2577-81 (2010) Article DOI: 10.1016/j.bmcl.2010.02.083 BindingDB Entry DOI: 10.7270/Q2WW7HT8
					More data for this Ligand-Target Pair