BDBM50315334 CHEMBL1089166::N-methyl-1-(8-phenylbenzofuro[3,2-d]pyrimidin-4-yl)pyrrolidin-3-amine

SMILES: CNC1CCN(C1)c1ncnc2c1oc1ccc(cc21)-c1ccccc1

InChI Key: InChIKey=KLCJXUWBFHXMOJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50315334 (CHEMBL1089166 | N-methyl-1-(8-phenylbenzofuro[3,2-...) Show SMILES CNC1CCN(C1)c1ncnc2c1oc1ccc(cc21)-c1ccccc1 Show InChI InChI=1S/C21H20N4O/c1-22-16-9-10-25(12-16)21-20-19(23-13-24-21)17-11-15(7-8-18(17)26-20)14-5-3-2-4-6-14/h2-8,11,13,16,22H,9-10,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Argenta Discovery Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]histamine dihydrochloride from human histamine H4 receptor after 2.5 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 2516-9 (2010) Article DOI: 10.1016/j.bmcl.2010.02.097 BindingDB Entry DOI: 10.7270/Q2CN74V3
					More data for this Ligand-Target Pair