BDBM50315337 CHEMBL1092881::N-methyl-4-(3-(methylamino)pyrrolidin-1-yl)benzofuro[3,2-d]pyrimidine-8-carboxamide

SMILES: CNC1CCN(C1)c1ncnc2c3cc(ccc3oc12)C(=O)NC

InChI Key: InChIKey=COMUBDYHRWXOAJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50315337 (CHEMBL1092881 | N-methyl-4-(3-(methylamino)pyrroli...) Show SMILES CNC1CCN(C1)c1ncnc2c3cc(ccc3oc12)C(=O)NC Show InChI InChI=1S/C17H19N5O2/c1-18-11-5-6-22(8-11)16-15-14(20-9-21-16)12-7-10(17(23)19-2)3-4-13(12)24-15/h3-4,7,9,11,18H,5-6,8H2,1-2H3,(H,19,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Argenta Discovery Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]histamine dihydrochloride from human histamine H4 receptor after 2.5 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 2516-9 (2010) Article DOI: 10.1016/j.bmcl.2010.02.097 BindingDB Entry DOI: 10.7270/Q2CN74V3
					More data for this Ligand-Target Pair