BDBM50315372 CHEMBL1088917::benzyl 2-benzyl-1-(methylsulfonyl)pyrrolidine-2-carboxylate

SMILES: CS(=O)(=O)N1CCCC1(Cc1ccccc1)C(=O)OCc1ccccc1

InChI Key: InChIKey=CJRFQEPRQVEVCZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 12 member 5 (Rattus norvegicus)	BDBM50315372 (CHEMBL1088917 | benzyl 2-benzyl-1-(methylsulfonyl)...) Show SMILES CS(=O)(=O)N1CCCC1(Cc1ccccc1)C(=O)OCc1ccccc1 Show InChI InChI=1S/C20H23NO4S/c1-26(23,24)21-14-8-13-20(21,15-17-9-4-2-5-10-17)19(22)25-16-18-11-6-3-7-12-18/h2-7,9-12H,8,13-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma SA Curated by ChEMBL					Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m...				Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C
					More data for this Ligand-Target Pair