BDBM50315482 CHEMBL1093897::N-(3-chlorophenylsulfonyl)-3-(3,3-difluoro-1-(naphthalen-2-ylmethyl)-2-oxoindolin-7-yl)acrylamide

SMILES: FC1(F)C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccc(Cl)c1

InChI Key: InChIKey=KFZLGIUUXIFPQJ-BUHFOSPRSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315482   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50315482 (CHEMBL1093897 | N-(3-chlorophenylsulfonyl)-3-(3,3-...) Show SMILES FC1(F)C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C28H19ClF2N2O4S/c29-22-8-4-9-23(16-22)38(36,37)32-25(34)14-13-20-7-3-10-24-26(20)33(27(35)28(24,30)31)17-18-11-12-19-5-1-2-6-21(19)15-18/h1-16H,17H2,(H,32,34)/b14-13+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50315482 (CHEMBL1093897 | N-(3-chlorophenylsulfonyl)-3-(3,3-...) Show SMILES FC1(F)C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C28H19ClF2N2O4S/c29-22-8-4-9-23(16-22)38(36,37)32-25(34)14-13-20-7-3-10-24-26(20)33(27(35)28(24,30)31)17-18-11-12-19-5-1-2-6-21(19)15-18/h1-16H,17H2,(H,32,34)/b14-13+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair