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SMILES: C[C@H](Nc1cc(ccn1)N(Cc1ccc(F)cc1)C(=O)N1CCC2C=CC=CC2C1)c1ccccc1

InChI Key: InChIKey=MZDVFSSURVBLHN-OIEGUCRUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315877   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50315877
PNG
(CHEMBL1090584 | N-(4-fluorobenzyl)-N-(2-((S)-1-phe...)
Show SMILES C[C@H](Nc1cc(ccn1)N(Cc1ccc(F)cc1)C(=O)N1CCC2C=CC=CC2C1)c1ccccc1 |r,c:26,28|
Show InChI InChI=1S/C30H31FN4O/c1-22(24-7-3-2-4-8-24)33-29-19-28(15-17-32-29)35(20-23-11-13-27(31)14-12-23)30(36)34-18-16-25-9-5-6-10-26(25)21-34/h2-15,17,19,22,25-26H,16,18,20-21H2,1H3,(H,32,33)/t22-,25?,26?/m0/s1
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Article
PubMed
n/an/a 1.11E+3n/an/an/an/an/an/a



Scios Inc.

Curated by ChEMBL


Assay Description
Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2556-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.088
BindingDB Entry DOI: 10.7270/Q2VT1S84
More data for this
Ligand-Target Pair