BDBM50315951 CHEMBL1093834::N-(2-(isopropylamino)pyrimidin-4-yl)-N-(piperidin-4-ylmethyl)-2,3-dihydrobenzofuran-5-carboxamide

SMILES: CC(C)Nc1nccc(n1)N(CC1CCNCC1)C(=O)c1ccc2OCCc2c1

InChI Key: InChIKey=CDDWNPXQRGKOOC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315951 (CHEMBL1093834 | N-(2-(isopropylamino)pyrimidin-4-y...) Show SMILES CC(C)Nc1nccc(n1)N(CC1CCNCC1)C(=O)c1ccc2OCCc2c1 Show InChI InChI=1S/C22H29N5O2/c1-15(2)25-22-24-11-7-20(26-22)27(14-16-5-9-23-10-6-16)21(28)18-3-4-19-17(13-18)8-12-29-19/h3-4,7,11,13,15-16,23H,5-6,8-10,12,14H2,1-2H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
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