BDBM50315954 (S)-N-(2-(1-methoxypropan-2-ylamino)pyrimidin-4-yl)-N-(piperidin-4-ylmethyl)-2,3-dihydrobenzofuran-5-carboxamide::CHEMBL1091287

SMILES: COC[C@H](C)Nc1nccc(n1)N(CC1CCNCC1)C(=O)c1ccc2OCCc2c1

InChI Key: InChIKey=NBGUZGNZRGJWIS-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315954 ((S)-N-(2-(1-methoxypropan-2-ylamino)pyrimidin-4-yl...) Show SMILES COC[C@H](C)Nc1nccc(n1)N(CC1CCNCC1)C(=O)c1ccc2OCCc2c1 |r| Show InChI InChI=1S/C23H31N5O3/c1-16(15-30-2)26-23-25-11-7-21(27-23)28(14-17-5-9-24-10-6-17)22(29)19-3-4-20-18(13-19)8-12-31-20/h3-4,7,11,13,16-17,24H,5-6,8-10,12,14-15H2,1-2H3,(H,25,26,27)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair