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SMILES: COC[C@H](C)Nc1nccc(n1)N(CCCCN)C(=O)c1ccc2OCCc2c1

InChI Key: InChIKey=TVPCUURVTHKRSS-HNNXBMFYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315960   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50315960
PNG
((S)-N-(4-aminobutyl)-N-(2-(1-methoxypropan-2-ylami...)
Show SMILES COC[C@H](C)Nc1nccc(n1)N(CCCCN)C(=O)c1ccc2OCCc2c1 |r|
Show InChI InChI=1S/C21H29N5O3/c1-15(14-28-2)24-21-23-10-7-19(25-21)26(11-4-3-9-22)20(27)17-5-6-18-16(13-17)8-12-29-18/h5-7,10,13,15H,3-4,8-9,11-12,14,22H2,1-2H3,(H,23,24,25)/t15-/m0/s1
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n/an/a 25n/an/an/an/an/an/a



Scios Inc.

Curated by ChEMBL


Assay Description
Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting

Bioorg Med Chem Lett 20: 2560-3 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.090
BindingDB Entry DOI: 10.7270/Q2BV7GS3
More data for this
Ligand-Target Pair