BDBM50315986 CHEMBL1090562::N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-(phenylsulfonylmethyl)cyclohexyl)-2,5-dioxopyrrolidin-3-yl)-3-(trifluoromethyl)benzamide

SMILES: CC(C)N(C)[C@@H]1CC[C@@H]([C@H](CS(=O)(=O)c2ccccc2)C1)N1C(=O)C[C@H](NC(=O)c2cccc(c2)C(F)(F)F)C1=O

InChI Key: InChIKey=MNJLHCYPHRHQLE-OZTAZYLFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50315986 (CHEMBL1090562 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...) Show SMILES CC(C)N(C)[C@@H]1CC[C@@H]([C@H](CS(=O)(=O)c2ccccc2)C1)N1C(=O)C[C@H](NC(=O)c2cccc(c2)C(F)(F)F)C1=O |r| Show InChI InChI=1S/C29H34F3N3O5S/c1-18(2)34(3)22-12-13-25(20(15-22)17-41(39,40)23-10-5-4-6-11-23)35-26(36)16-24(28(35)38)33-27(37)19-8-7-9-21(14-19)29(30,31)32/h4-11,14,18,20,22,24-25H,12-13,15-17H2,1-3H3,(H,33,37)/t20-,22+,24-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 mins				Bioorg Med Chem Lett 20: 2425-30 (2010) Article DOI: 10.1016/j.bmcl.2010.03.035 BindingDB Entry DOI: 10.7270/Q2ZK5GTM
					More data for this Ligand-Target Pair