BDBM50316000 (+/-)-tert-butyl 2-((R)-1-((1S,2R)-2-(4-(methylthio)benzamido)cyclohexyl)-2-oxopyrrolidin-3-ylcarbamoyl)-4-(trifluoromethyl)phenylcarbamate::CHEMBL1091266

SMILES: CSc1ccc(CN[C@@H]2CCCC[C@@H]2NC(=O)CNC(=O)c2cc(ccc2NC(=O)OC(C)(C)C)C(F)(F)F)cc1

InChI Key: InChIKey=LGCMOVRCUKEIRN-RPWUZVMVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50316000 ((+/-)-tert-butyl 2-((R)-1-((1S,2R)-2-(4-(methylthi...) Show SMILES CSc1ccc(CN[C@@H]2CCCC[C@@H]2NC(=O)CNC(=O)c2cc(ccc2NC(=O)OC(C)(C)C)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C29H37F3N4O4S/c1-28(2,3)40-27(39)36-22-14-11-19(29(30,31)32)15-21(22)26(38)34-17-25(37)35-24-8-6-5-7-23(24)33-16-18-9-12-20(41-4)13-10-18/h9-15,23-24,33H,5-8,16-17H2,1-4H3,(H,34,38)(H,35,37)(H,36,39)/t23-,24+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	312	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]-MCP1 from CCR2 in human PBMC after 30 mins				Bioorg Med Chem Lett 20: 2425-30 (2010) Article DOI: 10.1016/j.bmcl.2010.03.035 BindingDB Entry DOI: 10.7270/Q2ZK5GTM
					More data for this Ligand-Target Pair