BDBM50316152 CHEMBL4299749
SMILES: CCN(CC)CC.Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CNS(=O)(=O)c2n[nH]c3ccccc3c2=O)[C@@H](O)[C@H]1O
InChI Key: InChIKey=ROGKYOIYPKHIAW-GCHWKPKDSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2,3-dihydroxybenzoate-AMP ligase (Mycobacterium tuberculosis) | BDBM50316152 (CHEMBL4299749) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis recombinant salicylate ligase MbtA expressed in Escherichia coli using salicylic acid as substrate after 20 ... | ACS Med Chem Lett 9: 386-391 (2018) Article DOI: 10.1021/acsmedchemlett.8b00090 BindingDB Entry DOI: 10.7270/Q2RR21SH | |||||||||||
More data for this Ligand-Target Pair |