BDBM50316158 2,6-Diisopropylphenyl({4-(3-Methoxyphenyl)-1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl}carbonyl)sulfamate::CHEMBL1093025

SMILES: COc1cccc(c1)C1(CCN(CC1)c1nccc(n1)C(F)(F)F)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C

InChI Key: InChIKey=IYTYFFFPCZGGAT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50316158 (2,6-Diisopropylphenyl({4-(3-Methoxyphenyl)-1-[4-(t...) Show SMILES COc1cccc(c1)C1(CCN(CC1)c1nccc(n1)C(F)(F)F)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C Show InChI InChI=1S/C30H35F3N4O5S/c1-19(2)23-10-7-11-24(20(3)4)26(23)42-43(39,40)36-27(38)29(21-8-6-9-22(18-21)41-5)13-16-37(17-14-29)28-34-15-12-25(35-28)30(31,32)33/h6-12,15,18-20H,13-14,16-17H2,1-5H3,(H,36,38)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of rat macrophages ACAT				J Med Chem 53: 3284-95 (2010) Article DOI: 10.1021/jm901909p BindingDB Entry DOI: 10.7270/Q2639PWV
					More data for this Ligand-Target Pair