null

SMILES: O=C(Nc1ccccc1)Nc1ccc(cc1)-c1n[nH]cc1-c1ccnc2[nH]ccc12

InChI Key: InChIKey=JAYJZBXLNHGEKI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316490   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50316490 (CHEMBL1095192 | N-Phenyl-N'-{4-[4-(1H-pyrrolo[2,3-...) Show SMILES O=C(Nc1ccccc1)Nc1ccc(cc1)-c1n[nH]cc1-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C23H18N6O/c30-23(27-16-4-2-1-3-5-16)28-17-8-6-15(7-9-17)21-20(14-26-29-21)18-10-12-24-22-19(18)11-13-25-22/h1-14H,(H,24,25)(H,26,29)(H2,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human Aurora A				J Med Chem 53: 3973-4001 (2010) Article DOI: 10.1021/jm901870q BindingDB Entry DOI: 10.7270/Q27082CK
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50316490 (CHEMBL1095192 | N-Phenyl-N'-{4-[4-(1H-pyrrolo[2,3-...) Show SMILES O=C(Nc1ccccc1)Nc1ccc(cc1)-c1n[nH]cc1-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C23H18N6O/c30-23(27-16-4-2-1-3-5-16)28-17-8-6-15(7-9-17)21-20(14-26-29-21)18-10-12-24-22-19(18)11-13-25-22/h1-14H,(H,24,25)(H,26,29)(H2,27,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human Aurora B by rapid dilution method				J Med Chem 53: 3973-4001 (2010) Article DOI: 10.1021/jm901870q BindingDB Entry DOI: 10.7270/Q27082CK
					More data for this Ligand-Target Pair