BDBM50316554 1-(4-fluorophenyl)-1-(1-(4-fluorophenyl)-1H-indazol-5-yl)ethanol::CHEMBL1097475

SMILES: CC(O)(c1ccc(F)cc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1

InChI Key: InChIKey=AZRXVMYLZOAQMU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316554 (1-(4-fluorophenyl)-1-(1-(4-fluorophenyl)-1H-indazo...) Show SMILES CC(O)(c1ccc(F)cc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C21H16F2N2O/c1-21(26,15-2-5-17(22)6-3-15)16-4-11-20-14(12-16)13-24-25(20)19-9-7-18(23)8-10-19/h2-13,26H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair