BDBM50316848 5,6-Dimethyl-2-phenyl-3-prop-2-yn-1-ylthieno[2, 3-d]pyrimidin-4(3H)-one::CHEMBL1088398

SMILES: Cc1sc2nc(-c3ccccc3)n(CC#C)c(=O)c2c1C

InChI Key: InChIKey=QCAGZHQYMFWBKP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316848   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50316848 (5,6-Dimethyl-2-phenyl-3-prop-2-yn-1-ylthieno[2, 3-...) Show SMILES Cc1sc2nc(-c3ccccc3)n(CC#C)c(=O)c2c1C Show InChI InChI=1S/C17H14N2OS/c1-4-10-19-15(13-8-6-5-7-9-13)18-16-14(17(19)20)11(2)12(3)21-16/h1,5-9H,10H2,2-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatal membrane after 30 mins by scintillation counting				Eur J Med Chem 45: 1739-45 (2010) Article DOI: 10.1016/j.ejmech.2009.12.075 BindingDB Entry DOI: 10.7270/Q2N016NW
					More data for this Ligand-Target Pair