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BDBM50316979 4-((2-(Trimethylsilyl)ethoxy)carbonyloxy)benzyl 2-(2-(2,6-Dichlorophenylamino)phenyl)acetate::CHEMBL1088643

SMILES: C[Si](C)(C)CCOC(=O)Oc1ccc(COC(=O)Cc2ccccc2Nc2c(Cl)cccc2Cl)cc1

InChI Key: InChIKey=NBFYMPREQKPAFX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316979   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50316979
PNG
(4-((2-(Trimethylsilyl)ethoxy)carbonyloxy)benzyl 2-...)
Show SMILES C[Si](C)(C)CCOC(=O)Oc1ccc(COC(=O)Cc2ccccc2Nc2c(Cl)cccc2Cl)cc1
Show InChI InChI=1S/C27H29Cl2NO5Si/c1-36(2,3)16-15-33-27(32)35-21-13-11-19(12-14-21)18-34-25(31)17-20-7-4-5-10-24(20)30-26-22(28)8-6-9-23(26)29/h4-14,30H,15-18H2,1-3H3
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Article
PubMed
n/an/a 1.36E+3n/an/an/an/an/an/a



Lehigh University

Curated by ChEMBL


Assay Description
Inhibition of electric eel AChE by Ellman's method

Bioorg Med Chem Lett 20: 2987-90 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.102
BindingDB Entry DOI: 10.7270/Q2M045MV
More data for this
Ligand-Target Pair