BDBM50317448 7-Benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine::CHEMBL1095423

SMILES: Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12

InChI Key: InChIKey=WEUJYFZQFFQFND-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BRS3 (Homo sapiens (Human))	BDBM50317448 (7-Benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-...) Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12 Show InChI InChI=1S/C21H26N6/c22-19-18-16-9-12-26(13-15-7-3-1-4-8-15)14-17(16)21(23-20(18)25-24-19)27-10-5-2-6-11-27/h1,3-4,7-8H,2,5-6,9-14H2,(H3,22,23,24,25)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.53E+3	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at human BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay				Bioorg Med Chem Lett 20: 2785-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.065 BindingDB Entry DOI: 10.7270/Q2NZ88K4
					More data for this Ligand-Target Pair
Bombesin (RAT)	BDBM50317448 (7-Benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-...) Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12 Show InChI InChI=1S/C21H26N6/c22-19-18-16-9-12-26(13-15-7-3-1-4-8-15)14-17(16)21(23-20(18)25-24-19)27-10-5-2-6-11-27/h1,3-4,7-8H,2,5-6,9-14H2,(H3,22,23,24,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay				Bioorg Med Chem Lett 20: 2785-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.065 BindingDB Entry DOI: 10.7270/Q2NZ88K4
					More data for this Ligand-Target Pair