BDBM50317457 7-(4-Fluorobenzoyl)-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine::CHEMBL1098825

SMILES: Nc1n[nH]c2nc(N3CCCCC3)c3CN(CCc3c12)C(=O)c1ccc(F)cc1

InChI Key: InChIKey=RTRVVHLTJHRRNU-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bombesin (RAT)	BDBM50317457 (7-(4-Fluorobenzoyl)-5-(piperidin-1-yl)-6,7,8,9-tet...) Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(CCc3c12)C(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H23FN6O/c22-14-6-4-13(5-7-14)21(29)28-11-8-15-16(12-28)20(27-9-2-1-3-10-27)24-19-17(15)18(23)25-26-19/h4-7H,1-3,8-12H2,(H3,23,24,25,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay				Bioorg Med Chem Lett 20: 2785-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.065 BindingDB Entry DOI: 10.7270/Q2NZ88K4
					More data for this Ligand-Target Pair
BRS3 (Homo sapiens (Human))	BDBM50317457 (7-(4-Fluorobenzoyl)-5-(piperidin-1-yl)-6,7,8,9-tet...) Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(CCc3c12)C(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H23FN6O/c22-14-6-4-13(5-7-14)21(29)28-11-8-15-16(12-28)20(27-9-2-1-3-10-27)24-19-17(15)18(23)25-26-19/h4-7H,1-3,8-12H2,(H3,23,24,25,26)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at human BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay				Bioorg Med Chem Lett 20: 2785-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.065 BindingDB Entry DOI: 10.7270/Q2NZ88K4
					More data for this Ligand-Target Pair