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SMILES: Cc1nc(-c2cccc(\C=C\C(=O)NO)c2)n(CCc2ccccc2)c1C

InChI Key: InChIKey=MDWBJFGCVLUCHD-VAWYXSNFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317962   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50317962 (3-(3-(4,5-dimethyl-1-phenethyl-1H-imidazol-2-yl)ph...) Show SMILES Cc1nc(-c2cccc(\C=C\C(=O)NO)c2)n(CCc2ccccc2)c1C Show InChI InChI=1S/C22H23N3O2/c1-16-17(2)25(14-13-18-7-4-3-5-8-18)22(23-16)20-10-6-9-19(15-20)11-12-21(26)24-27/h3-12,15,27H,13-14H2,1-2H3,(H,24,26)/b12-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Takeda San Diego Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6				Bioorg Med Chem Lett 20: 3138-41 (2010) Article DOI: 10.1016/j.bmcl.2010.03.092 BindingDB Entry DOI: 10.7270/Q2514058
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50317962 (3-(3-(4,5-dimethyl-1-phenethyl-1H-imidazol-2-yl)ph...) Show SMILES Cc1nc(-c2cccc(\C=C\C(=O)NO)c2)n(CCc2ccccc2)c1C Show InChI InChI=1S/C22H23N3O2/c1-16-17(2)25(14-13-18-7-4-3-5-8-18)22(23-16)20-10-6-9-19(15-20)11-12-21(26)24-27/h3-12,15,27H,13-14H2,1-2H3,(H,24,26)/b12-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Takeda San Diego Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2				Bioorg Med Chem Lett 20: 3138-41 (2010) Article DOI: 10.1016/j.bmcl.2010.03.092 BindingDB Entry DOI: 10.7270/Q2514058
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50317962 (3-(3-(4,5-dimethyl-1-phenethyl-1H-imidazol-2-yl)ph...) Show SMILES Cc1nc(-c2cccc(\C=C\C(=O)NO)c2)n(CCc2ccccc2)c1C Show InChI InChI=1S/C22H23N3O2/c1-16-17(2)25(14-13-18-7-4-3-5-8-18)22(23-16)20-10-6-9-19(15-20)11-12-21(26)24-27/h3-12,15,27H,13-14H2,1-2H3,(H,24,26)/b12-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Takeda San Diego Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC8				Bioorg Med Chem Lett 20: 3138-41 (2010) Article DOI: 10.1016/j.bmcl.2010.03.092 BindingDB Entry DOI: 10.7270/Q2514058
					More data for this Ligand-Target Pair