BDBM50318004 2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(pyridin-2-yl)benzamide::CHEMBL1096073

SMILES: OC1(CNC(=O)c2cc(ccc2Cl)-c2ccccn2)CCCCCC1

InChI Key: InChIKey=GKCWCLHXKQQJNL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318004   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50318004 (2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(pyrid...) Show SMILES OC1(CNC(=O)c2cc(ccc2Cl)-c2ccccn2)CCCCCC1 Show InChI InChI=1S/C20H23ClN2O2/c21-17-9-8-15(18-7-3-6-12-22-18)13-16(17)19(24)23-14-20(25)10-4-1-2-5-11-20/h3,6-9,12-13,25H,1-2,4-5,10-11,14H2,(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer St. Louis Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced YO-PRO-1 uptake				Bioorg Med Chem Lett 20: 3107-11 (2010) Article DOI: 10.1016/j.bmcl.2010.03.094 BindingDB Entry DOI: 10.7270/Q2D50N4Q
					More data for this Ligand-Target Pair