BDBM50318006 2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(5-methoxypyridin-2-yl)benzamide::CHEMBL1098380

SMILES: COc1ccc(nc1)-c1ccc(Cl)c(c1)C(=O)NCC1(O)CCCCCC1

InChI Key: InChIKey=LPRKPVQIINGULW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50318006 (2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(5-met...) Show SMILES COc1ccc(nc1)-c1ccc(Cl)c(c1)C(=O)NCC1(O)CCCCCC1 Show InChI InChI=1S/C21H25ClN2O3/c1-27-16-7-9-19(23-13-16)15-6-8-18(22)17(12-15)20(25)24-14-21(26)10-4-2-3-5-11-21/h6-9,12-13,26H,2-5,10-11,14H2,1H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer St. Louis Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced YO-PRO-1 uptake				Bioorg Med Chem Lett 20: 3107-11 (2010) Article DOI: 10.1016/j.bmcl.2010.03.094 BindingDB Entry DOI: 10.7270/Q2D50N4Q
					More data for this Ligand-Target Pair