BDBM50318205 (Z)-2-(3-((3-Methoxy-7-(2-methoxyphenyl)-9-oxo-5H-benzo[h]-thiazolo[2,3-b]quinazolin-10(6H,7H,9H)-ylidene)methyl)phenoxy)-acetic Acid::CHEMBL1094443

SMILES: COC1CC2=C(N=c3s\c(=C/c4cccc(OCC(O)=O)c4)c(=O)n3C2c2ccccc2OC)c2ccccc12

InChI Key: InChIKey=QZXJLSBLISAQFO-YSMPRRRNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318205   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50318205 ((Z)-2-(3-((3-Methoxy-7-(2-methoxyphenyl)-9-oxo-5H-...) Show SMILES COC1CC2=C(N=c3s\c(=C/c4cccc(OCC(O)=O)c4)c(=O)n3C2c2ccccc2OC)c2ccccc12 |t:4,6| Show InChI InChI=1S/C31H26N2O6S/c1-37-24-13-6-5-12-22(24)29-23-16-25(38-2)20-10-3-4-11-21(20)28(23)32-31-33(29)30(36)26(40-31)15-18-8-7-9-19(14-18)39-17-27(34)35/h3-15,25,29H,16-17H2,1-2H3,(H,34,35)/b26-15-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human Bcl-XL				J Med Chem 53: 3465-79 (2010) Article DOI: 10.1021/jm901004c BindingDB Entry DOI: 10.7270/Q2QF8T11
					More data for this Ligand-Target Pair