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SMILES: CC(=O)Nc1ccccc1OCC1CN(C(=O)O1)c1ccccc1

InChI Key: InChIKey=YRZFKKJPUMNZDY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318309   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50318309
PNG
(CHEMBL1096052 | N-(2-((2-oxo-3-phenyloxazolidin-5-...)
Show SMILES CC(=O)Nc1ccccc1OCC1CN(C(=O)O1)c1ccccc1
Show InChI InChI=1S/C18H18N2O4/c1-13(21)19-16-9-5-6-10-17(16)23-12-15-11-20(18(22)24-15)14-7-3-2-4-8-14/h2-10,15H,11-12H2,1H3,(H,19,21)
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Similars
Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...

Bioorg Med Chem Lett 20: 3129-33 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.089
BindingDB Entry DOI: 10.7270/Q2Z038B7
More data for this
Ligand-Target Pair