BindingDB logo
myBDB logout

null

SMILES: CC(=O)Nc1ccc(OCC2CN(C(=O)O2)c2ccccc2)cc1

InChI Key: InChIKey=JKRGLRRAXCSVNF-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318311   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50318311
PNG
(CHEMBL1094430 | N-(4-((2-oxo-3-phenyloxazolidin-5-...)
Show SMILES CC(=O)Nc1ccc(OCC2CN(C(=O)O2)c2ccccc2)cc1
Show InChI InChI=1S/C18H18N2O4/c1-13(21)19-14-7-9-16(10-8-14)23-12-17-11-20(18(22)24-17)15-5-3-2-4-6-15/h2-10,17H,11-12H2,1H3,(H,19,21)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...

Bioorg Med Chem Lett 20: 3129-33 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.089
BindingDB Entry DOI: 10.7270/Q2Z038B7
More data for this
Ligand-Target Pair