BDBM50318414 7alpha-(1-Hydroxy-1-methyl-ethyl)-6,7,8,14-tetrahydro-6beta,14beta-endoethenooripavine::CHEMBL1094466
SMILES: CO[C@]12C=C[C@@]3(C[C@@H]1C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1C)c45
InChI Key: InChIKey=IXPHHHSWTVEWTP-VWUQPSBSSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50318414 (7alpha-(1-Hydroxy-1-methyl-ethyl)-6,7,8,14-tetrahy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Debrecen Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation counting | Bioorg Med Chem 18: 3535-42 (2010) Article DOI: 10.1016/j.bmc.2010.03.068 BindingDB Entry DOI: 10.7270/Q2JS9QK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50318414 (7alpha-(1-Hydroxy-1-methyl-ethyl)-6,7,8,14-tetrahy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Debrecen Curated by ChEMBL | Assay Description Displacement of [3H]deltorphin-2 from delta opioid receptor from Wistar rat brain by liquid scintillation counting | Bioorg Med Chem 18: 3535-42 (2010) Article DOI: 10.1016/j.bmc.2010.03.068 BindingDB Entry DOI: 10.7270/Q2JS9QK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (MOUSE) | BDBM50318414 (7alpha-(1-Hydroxy-1-methyl-ethyl)-6,7,8,14-tetrahy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 11.9 | n/a | n/a | n/a | n/a |
University of Debrecen Curated by ChEMBL | Assay Description Agonist activity at mu opioid receptor in Swiss albino mouse ileum assessed as inhibition of electrically-stimulated muscle contraction | Bioorg Med Chem 18: 3535-42 (2010) Article DOI: 10.1016/j.bmc.2010.03.068 BindingDB Entry DOI: 10.7270/Q2JS9QK7 | |||||||||||
More data for this Ligand-Target Pair |