BDBM50318526 CHEMBL1085864::H2N-ART-NH2

SMILES: [#6]-[#6@@H](-[#8])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7])-[#6](-[#7])=O

InChI Key: InChIKey=TXVGTYORMOSCJR-KZVJFYERSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (WDR5) (Homo sapiens (Human))	BDBM50318526 (CHEMBL1085864 | H2N-ART-NH2) Show SMILES [#6]-[#6@@H](-[#8])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7])-[#6](-[#7])=O |r| Show InChI InChI=1S/C13H27N7O4/c1-6(14)11(23)19-8(4-3-5-18-13(16)17)12(24)20-9(7(2)21)10(15)22/h6-9,21H,3-5,14H2,1-2H3,(H2,15,22)(H,19,23)(H,20,24)(H4,16,17,18)/t6-,7+,8-,9-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	2.73E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to WDR5 expressed in pLysS cells by optimized fluorescent polarization based competitive binding assay				J Med Chem 53: 5179-85 (2010) Article DOI: 10.1021/jm100139b BindingDB Entry DOI: 10.7270/Q2086678
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (WDR5) (Homo sapiens (Human))	BDBM50318526 (CHEMBL1085864 | H2N-ART-NH2) Show SMILES [#6]-[#6@@H](-[#8])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7])-[#6](-[#7])=O |r| Show InChI InChI=1S/C13H27N7O4/c1-6(14)11(23)19-8(4-3-5-18-13(16)17)12(24)20-9(7(2)21)10(15)22/h6-9,21H,3-5,14H2,1-2H3,(H2,15,22)(H,19,23)(H,20,24)(H4,16,17,18)/t6-,7+,8-,9-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to WDR5 expressed in pLysS cells by optimized fluorescent polarization based competitive binding assay				J Med Chem 53: 5179-85 (2010) Article DOI: 10.1021/jm100139b BindingDB Entry DOI: 10.7270/Q2086678
					More data for this Ligand-Target Pair