BDBM50318874 6-ethyl-3-(2-fluorophenethyl)-2-(2-hydroxyphenyl)-7-methylquinazolin-4(3H)-one::CHEMBL1083694

SMILES: CCc1cc2c(cc1C)nc(-c1ccccc1O)n(CCc1ccccc1F)c2=O

InChI Key: InChIKey=NWTFEEUZKJXPLN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318874   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50318874 (6-ethyl-3-(2-fluorophenethyl)-2-(2-hydroxyphenyl)-...) Show SMILES CCc1cc2c(cc1C)nc(-c1ccccc1O)n(CCc1ccccc1F)c2=O Show InChI InChI=1S/C25H23FN2O2/c1-3-17-15-20-22(14-16(17)2)27-24(19-9-5-7-11-23(19)29)28(25(20)30)13-12-18-8-4-6-10-21(18)26/h4-11,14-15,29H,3,12-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of CaSR				J Med Chem 53: 4332-53 (2010) Article DOI: 10.1021/jm9018756 BindingDB Entry DOI: 10.7270/Q21R6QPF
					More data for this Ligand-Target Pair