BDBM50319078 (E)-N-(4-(6-cyano-1-hydroxy-1H-benzo[d]imidazol-2-yl)phenyl)-3-(4-(methylthio)phenyl)acrylamide::CHEMBL1084861

SMILES: CSc1ccc(\C=C\C(=O)Nc2ccc(cc2)-c2nc3ccc(cc3n2O)C#N)cc1

InChI Key: InChIKey=UIJRIOCNRHHEEP-WLRTZDKTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319078   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Exoenzyme S synthesis regulatory protein exsA (Pseudomonas aeruginosa)	BDBM50319078 ((E)-N-(4-(6-cyano-1-hydroxy-1H-benzo[d]imidazol-2-...) Show SMILES CSc1ccc(\C=C\C(=O)Nc2ccc(cc2)-c2nc3ccc(cc3n2O)C#N)cc1 Show InChI InChI=1S/C24H18N4O2S/c1-31-20-10-2-16(3-11-20)5-13-23(29)26-19-8-6-18(7-9-19)24-27-21-12-4-17(15-25)14-22(21)28(24)30/h2-14,30H,1H3,(H,26,29)/b13-5+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Paratek Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activity				Bioorg Med Chem Lett 20: 3380-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.014 BindingDB Entry DOI: 10.7270/Q20R9PJ2
					More data for this Ligand-Target Pair